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Sunday, July 26, 2020 | History

1 edition of NTP technical report on the carcinogenesis studies of allyl isovalerate (CAS no. 2835-39-4) in F344/N rats and B6C3Fı mice (gavage study) found in the catalog.

NTP technical report on the carcinogenesis studies of allyl isovalerate (CAS no. 2835-39-4) in F344/N rats and B6C3Fı mice (gavage study)

NTP technical report on the carcinogenesis studies of allyl isovalerate (CAS no. 2835-39-4) in F344/N rats and B6C3Fı mice (gavage study)

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Published by U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, National Technical Information Service [distributor] in Bethesda, Md, Springfield, VA .
Written in English

    Subjects:
  • Carcinogenicity testing.,
  • Tube feeding.,
  • Toxicology -- Dose-response relationship.

  • Edition Notes

    Other titlesCarcinogenesis studies of allyl isovalerate., N.T.P. technical report on the carcinogenesis studies of allyl isovalerate.
    StatementNational Toxicology Program.
    SeriesTechnical report series / National Toxicology Program -- no. 253., NIH publication -- no. 83-2509., Technical report series (National Toxicology Program (U.S.)) -- no. 253., DHHS publication -- no. (NIH) 83-2509.
    ContributionsNational Toxicology Program (U.S.)
    The Physical Object
    Pagination185 p. :
    Number of Pages185
    ID Numbers
    Open LibraryOL18035546M

    Allyl isovalerate was of moderate acute oral and dermal toxicity in laboratory animals. Undiluted, it was moderately irritant to rabbit skin, but a dilute solution produced no irritation in man. An attempt to induce sensitization in volunteers using a dilute solution was unsuccessful.   Allyl isovalerate has a pleasant cherry or apple smell and is used in many fragranced products. The NTP tested it on animals and concluded that it was carcinogenic, producing leukaemia and lymphoma.

    Carcinogenesis Bioassay Technical Reports, Update No. 2 Google Scholar NTP National Toxicology Program Technical Report Series () No. , Tetra-chlorethylene. US Dept. Health & Human Services, NIH — Publ. No. Google ScholarCited by: 3. NTP Technical Report on the Carcinogenesis Bioassay of Allyl Isothiocyanate in F/N Rats and B6C3F1 Mice. NTP Technical Report TR Research Triangle Park, North Carolina and Bethesda, Maryland: National Toxicology Program.

    32 The compositions of allyl isothiocyanate (AITC) formulations differ depending on the source of AITC and 33 intended purpose of the product. At the molecular level, allyl isothiocyanate, with a molecular formula of 34 C 4 H 5 NS, is a volatile organic compound composed of carbon, hydrogen, nitrogen and sulfur atoms 35 (Chemical Book, ).File Size: KB. Part one provides full assessments of all relevant data on experimental carcinogenesis and cancer epidemiology for four chemicals: acrylonitrile, 1,3-butadiene, chloroprene, and dichloromethane. Of these, 1,3-butadiene remained classified as probably carcinogenic to humans, and dichloromethane remained classified as possibly carcinogenic to humans.


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NTP technical report on the carcinogenesis studies of allyl isovalerate (CAS no. 2835-39-4) in F344/N rats and B6C3Fı mice (gavage study) Download PDF EPUB FB2

Rows    Refer to the table below for information on NTP Technical Reports. The table presents an at-a-glance view of report numbers, chemical names, and conclusions. From the table, click any report number to view the related abstract, click any CASRN to view the testing status page, and click any date to view target organs and levels of evidence.

Allyl isovalerate: Target Organs and Levels of Evidence for TR Carcinogenesis Studies of Allyl Isovalerate (CASRN ) in F/N Rats and B6C3F1 Mice (Gavage Studies) Chemical (Study Title) NTP is located at the National Institute of Environmental Health Sciences.

N.T.P. technical report on the carcinogenesis studies of allyl isovalerate: Responsibility: National Toxicology Program. the National Toxicology Program (NTP) studies (NTP, b), which provide the most complete available assessment of the toxicity of allyl isovalerate.

Overall, it may be expected that since the chemical is approved in the U.S. for use as an organoleptic agent, widespread exposure at low levels may occur. allyl 3-methylbutanoate Butanoic acid, 3-methyl- 2-propenyl ester: State: SOLUTION (10% CCl4 FOR10% CS2 FOR CM-1) Instrument: DOW KBr FOREPRISM-GRATING: Instrument parameters: BLAZED AT, MICRON AND CHANGED AT, MICRON: Path length: CM, CM.

NTP (), National Toxicology Program Technical Report on the Carcinogenesis Studies ofAllylIsovalerate in FIN Rats and B6C3F1 Mice (Gavage Studies). NTP TRNational Institute of Environmental Health Sciences, National Institute of Health, Public Health Service, Department of Health and Human Services, Research Triangle Park, by: 2.

Allyl isovalerate is a fatty acid ester. Allyl isovalerate is a clear colorless to pale yellow liquid with overripe fruit odor and an apple taste.

(NTP, ) 2-Propenyl 3-methylbutanoate is a flavouring ingredient. Full text of "NTP technical report on the toxicology and carcinogenesis studies of tris(2-chloroethyl) phosphate (CAS no. ) in F/N rats and B6C3F1 mice (gavage studies)" See other formats.

Full text of "NTP technical report on the toxicology and carcinogenesis studies of barium chloride dihydrate (CAS no. ) in F/N rats and B6C3F́ mice (drinking water studies)" See other formats.

Complete Supply Chain: The perfect blend of products and services that bring your creativity to life. Sigma-Aldrich is a leading Life Science and High Technology company dedicated to providing high-quality, safe and certified flavor ingredients with transparent and easily accessible documentation to customers around the globe.

PharmacoL National Toxicology Program Report. (a). NTP Technical Report on the Carcinogenesis Bioassay of AlIyl lsothiocya- nate, DHHS Publication (NIH)Washington, DC. National Toxicology Program Report. (Ib). NTP Technical Report on the Carcinogenesis Bioassay of Stannous Chloride, DHHS Publication (NIH) Cited by: Author(s): National Toxicology Program (U.S.) Title(s): NTP technical report on the carcinogenesis studies of allyl isovalerate (CAS no.

) in F/N rats and B6C3F₁ mice (gavage study). NTP technical report on the toxicology and carcinogenesis studies of allyl glycidyl ether (CAS no. ) in Osborne-Mendel rats and B6C3Fı mice (inhalation studies) Author: Gary A Boorman ; National Toxicology Program (U.S.).

National Toxicology Program technical report series NTP Toxicology and Carcinogenesis Studies of Technical Grade Sodium Xylenesulfonate (CAS No. ) in F/N Rats and B6C3F1 Mice (Dermal Studies). PMID Under the conditions of these studies, allyl isovalerate was carcinogenic for F/N rats and B6C3F1 mice, causing increased incidences of hematopoietic system neoplasms (mononuclear-cell leukemia in male rats and lymphoma in female mice).

Levels of Evidence of Carcinogenicity: Male Rats: Positive Female Rats: Negativen female mice). *** CHEMICAL IDENTIFICATION *** RTECS NUMBER: NY CHEMICAL NAME: Isovaleric acid, allyl ester CAS REGISTRY NUMBER: BEILSTEIN REFERENCE NO.: REFERENCE: (Beilstein Handbook Reference) LAST UPDATED: DATA ITEMS CITED: 17 MOLECULAR FORMULA: C8-HO2 MOLECULAR.

Technical Report Series The cur - rent studies confirm that allyl isovalerate is hepa- totoxic in F/N rats TR Chlorinated Paraffins (C12, 60Chlorine) (CASRN Data from NTP studies show that a positive response in Salmonella is cur - rently the.

NTP () Technical report on the carcinogenesis bioassay of allyl isothiocyanate (CAS No. ) in F /N rats and B6C 3 F 1 mice (Gavage Study) NTP NIH Publication No.

US Department of Health and Human Services Google Scholar. Gulati, D., Witt, K., Anderson, B., Zeiger, E.,and Shelby, M. Chromosome aberration and sister chromatid exchange test in Chinese hamster ovary cells in vitro III. Comparative Results of Chemical Carcinogenicity Studies the results of these experiments in a series of Technical Reports.

This paper tabulates the results of the NCI/NTP studies. Allyl isovalerate + (14) Moreover, this study did not distinguish between genotoxic and non-genotoxic modes of carcinogenesis as there is a general lack of definitive mechanistic carcinogenicity data available to allow this distinction.

the NTP report on carcinogens found no evidence of carcinogenic activity Author: Matthew J Tate, Richard M Walmsley.N T P TECHNICAL REPORT ON THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF C.I.

PIGMENT RED 23 (CAS NO. ) IN F RATS AND B6C3Fl MICE (FEED STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. Box ResearchTrianglePark,NC November NTP TR N I H Publication No.

.ALLYL ISOVALERATE may react vigorously with strong oxidizing agents. STORAGE PRECAUTIONS: You should store this material in a refrigerator.

(NTP, ) Protective Clothing Since this chemical is a known or suspected carcinogen you should contact a physician for advice regarding the possible long term health effects and potential.